research interests

Overall, our research interests are:

identify dependency of pancreatic cancer cells and delineate the molecular and cellular mechanisms involved

(or identify intracellular signals that support the aberrant growth of pancreatic cancer cells in order to propose novel therapeutic avenues for pancreatic cancer)

Pictured as a mind map, here are the main themes of the lab: 

current projects

1) Define the role and the regulation of the transcription factor EB (TFEB), recognized as a master regulator of autophagy and lysosomal biogenesis, in the context of pancreatic epithelial cells 

2) Define the contribution of the DNA-PK complex in the regulation of autophagy

thanks to the granting agencies for their support